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Diabetes Management
Long-term Complications; Photo of doctor talking with patient

What Is Peripheral Neuropathy?

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Peripheral neuropathy is a disease of the nerves in your feet. It may make you unable to sense pain. Lack of pain makes you more likely to injure yourself without knowing it. But you can learn ways to protect your feet from injury.

When Nerves Are Diseased

Nerves in your feet carry signals to your brain. Your brain reads those signals and interprets them as sensations. When nerves in your feet are diseased, signals may never reach the brain. Or, signals may be confused. The result may be a lack of feeling in your feet or other symptoms of peripheral neuropathy.

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Symptoms Mask Pain

Symptoms of peripheral neuropathy begin in your toes. The symptoms slowly spread up your feet and legs as more nerve is affected. These symptoms may decrease sensation in your feet or mask pain. Without pain, you may not notice a cut or even a bone fracture. Cuts may become infected. Fractures may heal poorly and lead to foot deformity.

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Publication Source: Goetz, CG, Textbook of clinical neurology, 3rd ed., 2007, pp 825-6
Publication Source: Pascuzzi RM, Medical Clinics of North America 87(3), Peripheral neuropathies in clinical practice, May 1, 2003, pp 697-724
Publication Source: Wieman, TJ, American Journal of Surgery, 190(2), Principles of management: the diabetic foot, Aug 1, 2005, pp 295-9
Online Medical Reviewer: Bhattacharyya, Tim MD
Date Last Reviewed: 9/28/2004
Date Last Modified: 7/9/2002